Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report
Authors: Rabia Tahseen, Agha Muhammad Hammad Khan, Yumna Ahmed, Nasir Ali
Background: Treatment of locally advanced endometrial cancer in patients with transplanted pelvic kidney requires precautions because of its anatomical position next to target volumes. Case Presentation: We report a case of 42-year-old woman with a right renal transplant for 3 years diagnosed with endometrial cancer for which she underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy. Adjuvant Radiotherapy (RT) was planned through intensity modulated RT (IMRT) with 45 Gy in 25 fractions followed by vaginal brachytherapy (5 Gy × 2 sessions) . Planning with IMRT quantified a mean dose of 2 Gy and maximum dose of 10 Gy over the transplanted kidney. This dose was further reduced with a comparative plan of three-dimensional conformal RT (3DCRT), recording a mean dose of 1 Gy and maximum dose of 5 Gy to the transplanted kidney. 3DCRT plan was accepted and delivered. At 2-year follow-up, patient is disease free with normal renal function. Conclusion: In the presence of advanced techniques, 3DCRT is still a valid radiation technique to keep the critical organ dose under acceptable dose-volume constraints without compromising the target volume.
Keywords: Renal transplant, endometrium carcinoma, 3DCRT, IMRT, case report
Authors
Correspondence to:
Rabia Tahseen, Resident, Radiation Oncology, Basement, Ibn-e-Zuhr Building, Aga Khan University Hospital, Karachi, Pakistan Rabiya.tahseen6@gmail.com
Publication history:
Received 18 Mar 2021
Revised 12 Jun 2021
Accepted 15 Jun 2021
Published online 02 Jul 2021
Published in print 25 Jul 2021
Tahseen R, Khan AMH, Ahmed Y, Ali N. Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report. EJMCR. 2021; 5(7): 222-225. doi:
10.24911/ejmcr/173-1615803452
Tahseen R, Khan AMH, Ahmed Y, Ali N. Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report. https://www.ejmcr.com/?mno=64265 [Access: May 09, 2024]. doi:
10.24911/ejmcr/173-1615803452
Tahseen R, Khan AMH, Ahmed Y, Ali N. Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report. EJMCR. 2021; 5(7): 222-225. doi:
10.24911/ejmcr/173-1615803452
Tahseen R, Khan AMH, Ahmed Y, Ali N. Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report. EJMCR. (2021), [cited May 09, 2024]; 5(7): 222-225. doi:
10.24911/ejmcr/173-1615803452
Tahseen, R., Khan, . A. M. H., Ahmed, . Y. & Ali, . N. (2021) Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report. EJMCR, 5 (7), 222-225. doi:
10.24911/ejmcr/173-1615803452
Tahseen, Rabia, Agha Muhammad Hammad Khan, Yumna Ahmed, and Nasir Ali. 2021. Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report. European Journal of Medical Case Reports, 5 (7), 222-225. doi:
10.24911/ejmcr/173-1615803452
Tahseen, Rabia, Agha Muhammad Hammad Khan, Yumna Ahmed, and Nasir Ali. "Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report." European Journal of Medical Case Reports 5 (2021), 222-225. doi:
10.24911/ejmcr/173-1615803452
Tahseen, Rabia, Agha Muhammad Hammad Khan, Yumna Ahmed, and Nasir Ali. "Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report." European Journal of Medical Case Reports 5.7 (2021), 222-225. Print. doi:
10.24911/ejmcr/173-1615803452
Tahseen, R., Khan, . A. M. H., Ahmed, . Y. & Ali, . N. (2021) Adjuvant radiotherapy for endometrial cancer in a renal transplant patient - a case report. European Journal of Medical Case Reports, 5 (7), 222-225. doi:
10.24911/ejmcr/173-1615803452