Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report
Authors: Julie Tuypens, Jaro Van Zande, Klaas Van Den Heede, Sam Van Slycke
Background: Gallbladder metastasis from renal cell carcinoma (RCC) is extremely rare. Case Presentation: We present a case of metastasis of clear cell carcinoma to the gallbladder, mimicking acute cholecystitis on clinical exam, in an 80-year-old man 24 years after radical nephrectomy. Ultrasound showed an image compatible with acute cholecystitis with sludge in the gallbladder. An elective cholecystectomy was performed with an uneventful postoperative course. Histopathologic examination revealed a metastasis of clear-cell renal cell carcinoma. The clinical presentation of acute cholecystitis can mask an RCC metastasis to the gallbladder, even several years after initial nephrectomy. This makes qualitative anatomopathological examination essential, especially with a neoplasia in the medical history. Gallbladder metastasis from RCC is not necessarily linked to a poor outcome. A cholecystectomy is recommended whenever possible. Conclusion: This case highlights the importance of considering metastatic disease in the differential diagnosis of gallbladder masses and acute cholecystitis, even in patients with a history of treated primary tumors.
Keywords: Case Report, Gallbladder; Metastasis; Renal Cell Carcinoma.
Authors
Correspondence to:
Klaas Van Den Heede, Department of General and Endocrine Surgery, Onze-Lieve-Vrouw (OLV) Hospital Aalst-Asse-Ninove, Aalst, Belgium klaasvandenheede@hotmail.com
Publication history:
Received 24 Jan 2024
Revised 18 Feb 2024
Accepted 29 Mar 2024
Published online 30 Apr 2024
Published in print 13 May 2024
Tuypens J, Zande JV, Heede KVD, Slycke SV. Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report. EJMCR. 2024; 8(2): 37-40. doi:
10.24911/ejmcr.173-1706128578
Tuypens J, Zande JV, Heede KVD, Slycke SV. Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report. https://www.ejmcr.com/?mno=187897 [Access: May 20, 2024]. doi:
10.24911/ejmcr.173-1706128578
Tuypens J, Zande JV, Heede KVD, Slycke SV. Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report. EJMCR. 2024; 8(2): 37-40. doi:
10.24911/ejmcr.173-1706128578
Tuypens J, Zande JV, Heede KVD, Slycke SV. Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report. EJMCR. (2024), [cited May 20, 2024]; 8(2): 37-40. doi:
10.24911/ejmcr.173-1706128578
Tuypens, J., Zande, . J. V., Heede, . K. V. D. & Slycke, . S. V. (2024) Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report. EJMCR, 8 (2), 37-40. doi:
10.24911/ejmcr.173-1706128578
Tuypens, Julie, Jaro Van Zande, Klaas Van Den Heede, and Sam Van Slycke. 2024. Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report. European Journal of Medical Case Reports, 8 (2), 37-40. doi:
10.24911/ejmcr.173-1706128578
Tuypens, Julie, Jaro Van Zande, Klaas Van Den Heede, and Sam Van Slycke. "Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report." European Journal of Medical Case Reports 8 (2024), 37-40. doi:
10.24911/ejmcr.173-1706128578
Tuypens, Julie, Jaro Van Zande, Klaas Van Den Heede, and Sam Van Slycke. "Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report." European Journal of Medical Case Reports 8.2 (2024), 37-40. Print. doi:
10.24911/ejmcr.173-1706128578
Tuypens, J., Zande, . J. V., Heede, . K. V. D. & Slycke, . S. V. (2024) Late metastasis of a clear-cell renal cell carcinoma in the gallbladder as a possible cause of acute cholecystitis: a case report. European Journal of Medical Case Reports, 8 (2), 37-40. doi:
10.24911/ejmcr.173-1706128578