Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.
Authors: Roberto Adriano-Castro, Blas Flor-Lorente, Jorge Sancho-Muriel, Hanna Cholewa, Francisco Giner Segura
Background: The use of cation exchange resins such as sodium polystyrene sulfonate (SPS) in the treatment of hyperkalemia has been associated with potential damage to the gastrointestinal tract. Case Description: We present a clinical case of a 63-year-old male patient admitted following a single-lung transplant who presented a complex postoperative period associating renal failure and hyperkalemia, therefore administering SPS. 17 days afterward, the patient presented a clinical exacerbation with acute abdominal pain, due to a sigmoid perforation. The patient underwent urgent surgery, performing an open sigmoidectomy and terminal colostomy. The anatomo-pathological study of the surgical specimen revealed abundant SPS crystals in the depth of the colonic wall. Conclusions: Close patient surveillance and a high clinical suspicion are essential to prevent potentially fatal complications from the use of SPS. Due to low incidence of this complication, the evidence in literature is limited to case reports and retrospective studies.
Keywords: Sodium polystyrene sulfonate, Cation exchange resins, Intestinal perforation.
Authors
Correspondence to:
Roberto Adriano Castro, Colorectal Unit, University Hospital La Fe, Valencia, Spain robertoadc0@gmail.com
Publication history:
Received 22 Nov 2023
Accepted 16 Apr 2024
Published online 11 May 2024
Published in print 18 May 2024
Adriano-Castro R, Flor-Lorente B, Sancho-Muriel J, Hanna_Cholewa , Segura FG. Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.. EJMCR. 2024; 8(4): 68-71. doi:
10.24911/ejmcr.173-1700680736
Adriano-Castro R, Flor-Lorente B, Sancho-Muriel J, Hanna_Cholewa , Segura FG. Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.. https://www.ejmcr.com/?mno=178481 [Access: July 03, 2024]. doi:
10.24911/ejmcr.173-1700680736
Adriano-Castro R, Flor-Lorente B, Sancho-Muriel J, Hanna_Cholewa , Segura FG. Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.. EJMCR. 2024; 8(4): 68-71. doi:
10.24911/ejmcr.173-1700680736
Adriano-Castro R, Flor-Lorente B, Sancho-Muriel J, Hanna_Cholewa , Segura FG. Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.. EJMCR. (2024), [cited July 03, 2024]; 8(4): 68-71. doi:
10.24911/ejmcr.173-1700680736
Adriano-Castro, R., Flor-Lorente, . B., Sancho-Muriel, . J., Hanna_Cholewa, . & Segura, . F. G. (2024) Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.. EJMCR, 8 (4), 68-71. doi:
10.24911/ejmcr.173-1700680736
Adriano-Castro, Roberto, Blas Flor-Lorente, Jorge Sancho-Muriel, Hanna_Cholewa, and Francisco Giner Segura. 2024. Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.. European Journal of Medical Case Reports, 8 (4), 68-71. doi:
10.24911/ejmcr.173-1700680736
Adriano-Castro, Roberto, Blas Flor-Lorente, Jorge Sancho-Muriel, Hanna_Cholewa, and Francisco Giner Segura. "Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.." European Journal of Medical Case Reports 8 (2024), 68-71. doi:
10.24911/ejmcr.173-1700680736
Adriano-Castro, Roberto, Blas Flor-Lorente, Jorge Sancho-Muriel, Hanna_Cholewa, and Francisco Giner Segura. "Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.." European Journal of Medical Case Reports 8.4 (2024), 68-71. Print. doi:
10.24911/ejmcr.173-1700680736
Adriano-Castro, R., Flor-Lorente, . B., Sancho-Muriel, . J., Hanna_Cholewa, . & Segura, . F. G. (2024) Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report.. European Journal of Medical Case Reports, 8 (4), 68-71. doi:
10.24911/ejmcr.173-1700680736