Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan
Authors: Karim Khan, Aakif Ullah Khan, Banat Gul, Arif Ullah, Moiz Khan, Iftikhar Ahmad
Background: Photodynamic therapy (PDT) offers an effective treatment in several dermatological disorders. Herein, PDT has been assessed for the treatment of cutaneous leishmaniasis (CL) in a series of six patients from Pakistan. Cases Presentation: Six patients presenting with CL lesions at different face sites (i.e., cheek, nose, and lip) were treated with methylaminolevulinate-based PDT. The treatment was completed in three sessions, where a light dose of 75 J/cm2 was delivered through a low power (300 mW) red laser (wavelength = 635 nm) in each session. Results: The assessment of the disease at 10 months follow-up illustrated complete response in 5 patients, while partial response in 1 patient. Conclusion: This case series study demonstrated that PDT may offer a viable treatment option to the CL patients.
Keywords: cutaneous leishmaniasis, PDT, dermatology, laser therapy, protozoan parasite
Authors
Correspondence to:
Iftikhar Ahmad, Institute of Radiotherapy and Nuclear Medicine (IRNUM), University Campus, Peshawar, Pakistan iahmadmp@gmail.com
Publication history:
Received 05 Dec 2020
Revised 19 Jun 2021
Accepted 23 Jun 2021
Published online 05 Jul 2021
Published in print 25 Jul 2021
Khan K, Khan AU, Gul B, Ullah A, Khan M, Ahmad I. Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan. EJMCR. 2021; 5(7): 203-208. doi:
10.24911/ejmcr/173-1606794043
Khan K, Khan AU, Gul B, Ullah A, Khan M, Ahmad I. Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan. https://www.ejmcr.com/?mno=16656 [Access: May 09, 2024]. doi:
10.24911/ejmcr/173-1606794043
Khan K, Khan AU, Gul B, Ullah A, Khan M, Ahmad I. Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan. EJMCR. 2021; 5(7): 203-208. doi:
10.24911/ejmcr/173-1606794043
Khan K, Khan AU, Gul B, Ullah A, Khan M, Ahmad I. Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan. EJMCR. (2021), [cited May 09, 2024]; 5(7): 203-208. doi:
10.24911/ejmcr/173-1606794043
Khan, K., Khan, . A. U., Gul, . B., Ullah, . A., Khan, . M. & Ahmad, . I. (2021) Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan. EJMCR, 5 (7), 203-208. doi:
10.24911/ejmcr/173-1606794043
Khan, Karim, Aakif Ullah Khan, Banat Gul, Arif Ullah, Moiz Khan, and Iftikhar Ahmad. 2021. Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan. European Journal of Medical Case Reports, 5 (7), 203-208. doi:
10.24911/ejmcr/173-1606794043
Khan, Karim, Aakif Ullah Khan, Banat Gul, Arif Ullah, Moiz Khan, and Iftikhar Ahmad. "Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan." European Journal of Medical Case Reports 5 (2021), 203-208. doi:
10.24911/ejmcr/173-1606794043
Khan, Karim, Aakif Ullah Khan, Banat Gul, Arif Ullah, Moiz Khan, and Iftikhar Ahmad. "Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan." European Journal of Medical Case Reports 5.7 (2021), 203-208. Print. doi:
10.24911/ejmcr/173-1606794043
Khan, K., Khan, . A. U., Gul, . B., Ullah, . A., Khan, . M. & Ahmad, . I. (2021) Photodynamic therapy for the treatment of cutaneous leishmaniasis: a case series from Pakistan. European Journal of Medical Case Reports, 5 (7), 203-208. doi:
10.24911/ejmcr/173-1606794043