Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review
Authors: Arif Kodza, Bana Hadid, Sumatha Channapatna Suresh, Iqra Aftab, Elif Yakut, Aleksander Feoktistov, Eugeniya Golub
Background: Sarcoidosis is a multi-system inflammatory disorder characterized by non-caseating granulomas with predominantly lung manifestations that can cause restrictive or, less commonly, obstructive lung disease. Rarely is pneumothorax a manifestation of sarcoidosis; it has been reported as an early finding in sarcoidosis, but it is typically attributed to ruptured bullae, cysts, or pleural granulomas. Case presentation: We present a unique case of spontaneous pneumothorax attributed to biopsy-proven sarcoid disease in a patient with no prior history of pulmonary complications. The patient’s rapid development of novel pulmonary sequelae necessitates treatment of sarcoidosis early in disease course. Conclusion: We recommend a treatment plan of appropriate chest tube placement in the affected lung(s) and prompt steroid therapy for patients with sarcoidosis presenting with a pneumothorax. We also review the literature for the etiology, pathophysiology, and presentation of pneumothorax in sarcoidosis, treatment of this sequela, and pulmonary function test findings in these patients.
Keywords: sarcoidosis, pneumothorax, bullous disease, restrictive lung disease, steroid therapy.
Authors
Correspondence to:
Arif Kodza, New York University Langone Hospital - Brooklyn, Department of Internal Medicine, Brooklyn, USA arif.kodza@nyulangone.org
Publication history:
Received 17 May 2023
Revised 04 Dec 2023
Accepted 10 Feb 2024
Published online 02 May 2024
Published in print 18 May 2024
Kodza A, Hadid B, Suresh SC, Aftab I, Yakut E, Feoktistov A, Golub E. Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review. EJMCR. 2024; 8(5): 99-103. doi:
10.24911/ejmcr.173-1684354133
Kodza A, Hadid B, Suresh SC, Aftab I, Yakut E, Feoktistov A, Golub E. Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review. https://www.ejmcr.com/?mno=153683 [Access: July 03, 2024]. doi:
10.24911/ejmcr.173-1684354133
Kodza A, Hadid B, Suresh SC, Aftab I, Yakut E, Feoktistov A, Golub E. Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review. EJMCR. 2024; 8(5): 99-103. doi:
10.24911/ejmcr.173-1684354133
Kodza A, Hadid B, Suresh SC, Aftab I, Yakut E, Feoktistov A, Golub E. Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review. EJMCR. (2024), [cited July 03, 2024]; 8(5): 99-103. doi:
10.24911/ejmcr.173-1684354133
Kodza, A., Hadid, . B., Suresh, . S. C., Aftab, . I., Yakut, . E., Feoktistov, . A. & Golub, . E. (2024) Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review. EJMCR, 8 (5), 99-103. doi:
10.24911/ejmcr.173-1684354133
Kodza, Arif, Bana Hadid, Sumatha Channapatna Suresh, Iqra Aftab, Elif Yakut, Aleksander Feoktistov, and Eugeniya Golub. 2024. Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review. European Journal of Medical Case Reports, 8 (5), 99-103. doi:
10.24911/ejmcr.173-1684354133
Kodza, Arif, Bana Hadid, Sumatha Channapatna Suresh, Iqra Aftab, Elif Yakut, Aleksander Feoktistov, and Eugeniya Golub. "Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review." European Journal of Medical Case Reports 8 (2024), 99-103. doi:
10.24911/ejmcr.173-1684354133
Kodza, Arif, Bana Hadid, Sumatha Channapatna Suresh, Iqra Aftab, Elif Yakut, Aleksander Feoktistov, and Eugeniya Golub. "Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review." European Journal of Medical Case Reports 8.5 (2024), 99-103. Print. doi:
10.24911/ejmcr.173-1684354133
Kodza, A., Hadid, . B., Suresh, . S. C., Aftab, . I., Yakut, . E., Feoktistov, . A. & Golub, . E. (2024) Spontaneous Pneumothorax as an Early Manifestation of Pulmonary Sarcoidosis: a case-based review. European Journal of Medical Case Reports, 8 (5), 99-103. doi:
10.24911/ejmcr.173-1684354133