EJMCR. 2020; 4(9): 285-287

An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration

Authors: Marta De Castro Martinez, Cristina Castillo Maza.

ABSTRACT

Background: The main use of Granulocyte colony stimulating factor (G-CSF) is stem cell mobilization in neutropenic patients and healthy donors as well as for engraftment. Most of their secondary effects are mild and temporary; however, there is a relation between spontaneous splenic rupture and G-CSF treatment. Case Presentation: We report a case of an 88-year old man, who presented with a spontaneous splenic rupture after use of G-CSF. Conclusion: Although it is an uncommon side effect, the mortality is very high, so clinicians should be aware of the importance about maintaining a high index of suspicion for this condition.

Keywords:
Case report, spleen, hemoperitoneum, shock, neutropenia.


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An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration


Authors
Marta De Castro Martinez
Internal Medicine Service, Hospital Universitario 12 de Octubre. Madrid, Spain
PubMed articlesGoogle scholar articles

Cristina Castillo Maza
Internal Medicine Service, Hospital Universitario 12 de Octubre. Madrid, Spain.
PubMed articlesGoogle scholar articles


Correspondence to:
. Marta De Castro Martinez, Internal Medicine Service, Hospital Universitario 12 de Octubre, Madrid, Spain.; martadecastro84@gmail.com

Publication history
Received 29 Aug 2019
Revised 06 Apr 2020
Accepted 06 May 2020
Published online 14 Oct 2020
Published in print 17 Oct 2020

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Pubmed Style

Martinez MDC, Maza CC. An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration. EJMCR. 2020; 4(9): 285-287. doi:10.24911/ejmcr/173-1567102492


Web Style

Martinez MDC, Maza CC. An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration. https://www.ejmcr.com/?mno=63378 [Access: October 23, 2020]. doi:10.24911/ejmcr/173-1567102492


AMA (American Medical Association) Style

Martinez MDC, Maza CC. An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration. EJMCR. 2020; 4(9): 285-287. doi:10.24911/ejmcr/173-1567102492


Vancouver/ICMJE Style

Martinez MDC, Maza CC. An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration. EJMCR. (2020), [cited October 23, 2020]; 4(9): 285-287. doi:10.24911/ejmcr/173-1567102492


Harvard Style

Martinez, M. D. C. & Maza, . C. C. (2020) An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration. EJMCR, 4 (9), 285-287. doi:10.24911/ejmcr/173-1567102492


Turabian Style

Martinez, Marta De Castro, and Cristina Castillo Maza. 2020. An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration. European Journal of Medical Case Reports, 4 (9), 285-287. doi:10.24911/ejmcr/173-1567102492


Chicago Style

Martinez, Marta De Castro, and Cristina Castillo Maza. "An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration." European Journal of Medical Case Reports 4 (2020), 285-287. doi:10.24911/ejmcr/173-1567102492


MLA (The Modern Language Association) Style

Martinez, Marta De Castro, and Cristina Castillo Maza. "An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration." European Journal of Medical Case Reports 4.9 (2020), 285-287. Print. doi:10.24911/ejmcr/173-1567102492


APA (American Psychological Association) Style

Martinez, M. D. C. & Maza, . C. C. (2020) An 88-year old man with spontaneous splenic rupture after granulocyte colony stimulating factor administration. European Journal of Medical Case Reports, 4 (9), 285-287. doi:10.24911/ejmcr/173-1567102492


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