EJMCR. 2020; 4(4): 123-125

Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins

Authors: Tahir Iqbal, Wajahat Sultan Baig, Saamia Arshad, Sara Altaf Awan.

ABSTRACT

Background: We, here, describe the case of Systemic Lupus Erythematosus (SLE) with pancytopenia, refractory to steroids immunosuppressive therapy, and plasmapharesis that ultimately responded to intravenous immunoglobulins (IVIG). To the best of our knowledge, very few cases of this type have been reported in literature. Case presentation: A 40-year-old female presented with complaints of hematemesis, hematochezia, gum bleed, epistaxis, menorrhagia, and fever. After careful examination and investigation she was diagnosed with SLE associated with pancytopenia refractory to conventional means of treatment. Pancytopenia responds normally to steroids and immunosuppressive agents in these patients however our patient responded only to IVIG. Conclusion: This case report highlights the fact that early use of Intravenous immunoglobulins in patients of SLE with severe and refractory pancytopenia can prevent morbidity and mortality..

Keywords:
SLE, pancytopenia, intravenous immunoglobulins, case report.


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Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins


Authors
Tahir Iqbal
Department of Medicine, Shifa College of Medicine (Shifa Tameer e Millat University), Consultant Medical Specialist, Shifa International Hospital, Islamabad, Pakistan
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Wajahat Sultan Baig
Senior Registrar, Department of Medicine, Shifa College of Medicine(Shifa Tameer e Millat University), Islamabad, Pakistan
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Saamia Arshad
4th year Medical student in MBBS Program, Ayub Medical College, Abbottabad, Pakistan
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Sara Altaf Awan
Post Graduate Resident, Haematology Department, Shifa International Hospital, Islamabad, Pakistan
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Correspondence to:
. Wajahat Sultan Baig, Senior Registrar, Department of Medicine, Shifa College of Medicine(Shifa Tameer e Millat University), Islamabad, Pakistan.; wajahat_sultan@yahoo.com

Publication history
Received 26 Aug 2019
Accepted 23 Apr 2020
Published online 05 May 2020
Published in print 24 May 2020

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Pubmed Style

Iqbal T, Baig WS, Arshad S, Awan SA. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. EJMCR. 2020; 4(4): 123-125. doi:10.24911/ejmcr/173-1566719209


Web Style

Iqbal T, Baig WS, Arshad S, Awan SA. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. https://www.ejmcr.com/?mno=62630 [Access: July 11, 2020]. doi:10.24911/ejmcr/173-1566719209


AMA (American Medical Association) Style

Iqbal T, Baig WS, Arshad S, Awan SA. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. EJMCR. 2020; 4(4): 123-125. doi:10.24911/ejmcr/173-1566719209


Vancouver/ICMJE Style

Iqbal T, Baig WS, Arshad S, Awan SA. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. EJMCR. (2020), [cited July 11, 2020]; 4(4): 123-125. doi:10.24911/ejmcr/173-1566719209


Harvard Style

Iqbal, T., Baig, . W. S., Arshad, . S. & Awan, . S. A. (2020) Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. EJMCR, 4 (4), 123-125. doi:10.24911/ejmcr/173-1566719209


Turabian Style

Iqbal, Tahir, Wajahat Sultan Baig, Saamia Arshad, and Sara Altaf Awan. 2020. Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. European Journal of Medical Case Reports, 4 (4), 123-125. doi:10.24911/ejmcr/173-1566719209


Chicago Style

Iqbal, Tahir, Wajahat Sultan Baig, Saamia Arshad, and Sara Altaf Awan. "Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins." European Journal of Medical Case Reports 4 (2020), 123-125. doi:10.24911/ejmcr/173-1566719209


MLA (The Modern Language Association) Style

Iqbal, Tahir, Wajahat Sultan Baig, Saamia Arshad, and Sara Altaf Awan. "Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins." European Journal of Medical Case Reports 4.4 (2020), 123-125. Print. doi:10.24911/ejmcr/173-1566719209


APA (American Psychological Association) Style

Iqbal, T., Baig, . W. S., Arshad, . S. & Awan, . S. A. (2020) Systemic Lupus Erythematosus associated refractory pancytopenia responding only to intravenous immunoglobulins. European Journal of Medical Case Reports, 4 (4), 123-125. doi:10.24911/ejmcr/173-1566719209


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