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Authors: Benayad Aourarh , Tarik Adioui , Sanaa Berrag , Mouna Tamzaourte , Aziz Aourarh

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Abstract

Background: Acute pancreatitis (AP) is a common cause of hospitalization in gastroenterology. Drug-induced AP is a rare event, and only a few cases of corticosteroids induced AP are described in the literature. Case Presentation: A 39-year-old woman with ankylosing spondylitis was hospitalized for an acute epigastric pain with vomiting 3 days after receiving a methylprednisolone bolus for an outbreak of her chronic disease. Her serum lipase concentration was found to be particularly elevated. She was then diagnosed of AP. An abdominal non-contrast CT demonstrated an exudative pancreatitis with a peripancreatic collection. The liver enzymes, her corrected calcium, and lipid profile were normal. An autoimmunity IgG4 screening was also found negative. The magnetic resonance imaging of the biliary tract found a normal pancreatic gland with a non-dilated common bile duct. Conclusion: Due to the events chronology, the diagnosis of a methylprednisolone induced AP was retained after the exclusion of other causes of pancreatitis. It is important to think about this etiology when the most common causes have been ruled out.

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Keywords: Acute pancreatitis, Methylprednisolone, green

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