Case Report
Published: Nov 03, 2025 | DOI: 10.24911/ejmcr.9-2277
The importance of laboratory analyses in unmasking parathyroid adenoma in a patient with breast cancer: a case report of persistent hypercalcaemia with low vitamin D status
Authors:
Anna Zsófia Puskás
, Enikő Nemes-Nagy
, Róbert Nemes-Nagy
, Melinda Kolcsár
Article Info
Authors
Anna Zsófia Puskás
"George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș
Enikő Nemes-Nagy
"George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș
Róbert Nemes-Nagy
"George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș
Melinda Kolcsár
"George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș
Publication History
Received: July 06, 2025
Accepted: September 22, 2025
Published: November 03, 2025
Abstract
Background: Parathyroid adenoma is a frequent cause of hyperparathyroidism. Its association with D hypovitaminosis can complicate this pathological state, especially in case of delayed surgical intervention.
Case presentation: This case report presents a 77-year-old female patient with a complex medical history including dyslipidemia, hypertension, who developed primary hyperparathyroidism due to a parathyroid adenoma. The persistent hypercalcemia, elevated parathyroid hormone (PTH), and parathyroid scintigraphy led to the diagnosis, but the low 25-hydroxyvitamin D level complicated the picture. Due to personal decisions and the COVID-19 pandemic, surgery was delayed for six years, resulting in complications such as vitamin D deficiency-induced immunosuppression and osteoporosis. Post-surgical outcomes were favorable, with normalization of biochemical markers and stabilization of comorbid conditions.
Conclusion: This case highlights that timely multidisciplinary management is essential in primary hyperthyroidism, as surgical delay worsens complications, yet parathyroidectomy can still reverse outcomes even after years of progression.
Keywords: case report, hypercalcemia, low vitamin D status, primary hyperparathyroidism
Pubmed Style
Anna Zsófia Puskás, Enikő Nemes-Nagy, Róbert Nemes-Nagy, Melinda Kolcsár. The importance of laboratory analyses in unmasking parathyroid adenoma in a patient with breast cancer: a case report of persistent hypercalcaemia with low vitamin D status. EJMCR. 2025; 03 (November 2025): -. doi:10.24911/ejmcr.9-2277
Web Style
Anna Zsófia Puskás, Enikő Nemes-Nagy, Róbert Nemes-Nagy, Melinda Kolcsár. The importance of laboratory analyses in unmasking parathyroid adenoma in a patient with breast cancer: a case report of persistent hypercalcaemia with low vitamin D status. https://ejmcr.com/index.php/articles/2277 [Access: November 08, 2025]. doi:10.24911/ejmcr.9-2277
AMA (American Medical Association) Style
Anna Zsófia Puskás, Enikő Nemes-Nagy, Róbert Nemes-Nagy, Melinda Kolcsár. The importance of laboratory analyses in unmasking parathyroid adenoma in a patient with breast cancer: a case report of persistent hypercalcaemia with low vitamin D status. EJMCR. 2025; 03 (November 2025): -. doi:10.24911/ejmcr.9-2277
Vancouver/ICMJE Style
Anna Zsófia Puskás, Enikő Nemes-Nagy, Róbert Nemes-Nagy, Melinda Kolcsár. The importance of laboratory analyses in unmasking parathyroid adenoma in a patient with breast cancer: a case report of persistent hypercalcaemia with low vitamin D status. EJMCR. (2025), [cited November 08, 2025]; 03 (November 2025): -. doi:10.24911/ejmcr.9-2277
Harvard Style
Anna Zsófia Puskás, Enikő Nemes-Nagy, Róbert Nemes-Nagy, Melinda Kolcsár (2025) The importance of laboratory analyses in unmasking parathyroid adenoma in a patient with breast cancer: a case report of persistent hypercalcaemia with low vitamin D status. EJMCR, 03 (November 2025): -. doi:10.24911/ejmcr.9-2277
Chicago Style
Anna Zsófia Puskás, Enikő Nemes-Nagy, Róbert Nemes-Nagy, Melinda Kolcsár. "The importance of laboratory analyses in unmasking parathyroid adenoma in a patient with breast cancer: a case report of persistent hypercalcaemia with low vitamin D status." 03 (2025), -. doi:10.24911/ejmcr.9-2277
MLA (The Modern Language Association) Style
Anna Zsófia Puskás, Enikő Nemes-Nagy, Róbert Nemes-Nagy, Melinda Kolcsár. "The importance of laboratory analyses in unmasking parathyroid adenoma in a patient with breast cancer: a case report of persistent hypercalcaemia with low vitamin D status." 03.November 2025 (2025), -. Print. doi:10.24911/ejmcr.9-2277
APA (American Psychological Association) Style
Anna Zsófia Puskás, Enikő Nemes-Nagy, Róbert Nemes-Nagy, Melinda Kolcsár (2025) The importance of laboratory analyses in unmasking parathyroid adenoma in a patient with breast cancer: a case report of persistent hypercalcaemia with low vitamin D status. , 03 (November 2025), -. doi:10.24911/ejmcr.9-2277