Pulmonary embolism in iatrogenic Cushing’s syndrome: a case report
Authors: May Thu Kyaw
Background: Patients with Cushing’s syndrome have an increased risk of thrombosis due to acquired hypercoagulability. Case Presentation: A 54-year-old obese female, with underlying iatrogenic Cushing’s syndrome (ICS), presented with a sudden onset of dyspnea and circulatory collapse. Computed tomography pulmonary angiogram confirmed acute massive pulmonary embolism (PE). She showed marked improvement after treatment with anticoagulation. Conclusion: This case demonstrates the clinical presentations and pathophysiology of Cushing’s syndrome (CS). CS patients are prone to thrombosis due to disturbance in all three components of Virchow’s triad. PE is one of the leading causes of mortality in CS. Clinicians should be aware of this serious, but less recognized, complication when a patient with CS presents with acute circulatory collapse. Anticoagulants remain the mainstay of treatment in ICS complicated by PE.
Keywords: Cushing’s syndrome, corticosteroids, thrombosis, pulmonary embolism, anticoagulation, case report
Authors
Correspondence to:
May Thu Kyaw, Heart and Vascular Centre, Victoria Hospital, Yangon, Myanmar eaindray.phoopwintkyi517@gmail.com
Publication history:
Received 07 Dec 2021
Revised 19 Mar 2022
Accepted 16 Apr 2022
Published online 27 Apr 2022
Published in print 12 Aug 2022
May Thu Kyaw. Pulmonary embolism in iatrogenic Cushing’s syndrome: a case report. https://www.ejmcr.com/?mno=40175 [Access: April 24, 2024]. doi:
10.24911/ejmcr/173-1638855099
May Thu Kyaw. Pulmonary embolism in iatrogenic Cushing’s syndrome: a case report. EJMCR. (2022), [cited April 24, 2024]; 6(4): 58-63. doi:
10.24911/ejmcr/173-1638855099
May Thu Kyaw. 2022. Pulmonary embolism in iatrogenic Cushing’s syndrome: a case report. European Journal of Medical Case Reports, 6 (4), 58-63. doi:
10.24911/ejmcr/173-1638855099
May Thu Kyaw. "Pulmonary embolism in iatrogenic Cushing’s syndrome: a case report." European Journal of Medical Case Reports 6 (2022), 58-63. doi:
10.24911/ejmcr/173-1638855099
May Thu Kyaw. "Pulmonary embolism in iatrogenic Cushing’s syndrome: a case report." European Journal of Medical Case Reports 6.4 (2022), 58-63. Print. doi:
10.24911/ejmcr/173-1638855099
May Thu Kyaw (2022) Pulmonary embolism in iatrogenic Cushing’s syndrome: a case report. European Journal of Medical Case Reports, 6 (4), 58-63. doi:
10.24911/ejmcr/173-1638855099