Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report
Authors: Paul El Meouchy, Noha Bejjani, Maroun Abou Nader, Roula Farah
Background: Mature teratomas are common tumors in the pediatric population. They can arise in the central nervous system and often require surgical resection. They are classified as non-germinomatous germ cell tumors and their recurrence are extremely rare. Case Presentation: We are reporting the case of a 6-year-old boy who was diagnosed with mature pineal teratoma after he presented with signs of acute hydrocephalus. Histopathology did not reveal any other germ cell tumor component. He underwent a complete resection of the mass, with no adjuvant chemotherapy. Nine years post-operatively, magnetic resonance imaging results showed recurrence of the pineal tumor as a germinoma. Chemotherapy and radiotherapy resulted in significant shrinkage of the mass and resolution of the clinical symptoms. Conclusion: This case illustrates the possibility of the late recurrence of a germinoma after the complete removal of a mature intracranial teratoma. It also raises the issue of whether mature teratomas should be treated with adjuvant therapy after surgical resection to prevent their recurrence as another germ cell tumor.
Keywords: Germinoma, mature teratoma, germ cell tumor, pineal teratoma, case report
Authors
Correspondence to:
Roula Farah, Department of Pediatrics, Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon dr.roulafarah@gmail.com
Publication history:
Received 16 May 2021
Revised 12 Oct 2021
Accepted 13 Oct 2021
Published online 02 Jan 2022
Published in print 12 Jan 2022
Meouchy PE, Bejjani N, Nader MA, Farah R. Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report. EJMCR. 2021; 5(12): 334-336. doi:
10.24911/ejmcr/173-1621160240
Meouchy PE, Bejjani N, Nader MA, Farah R. Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report. https://www.ejmcr.com/?mno=81653 [Access: April 18, 2024]. doi:
10.24911/ejmcr/173-1621160240
Meouchy PE, Bejjani N, Nader MA, Farah R. Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report. EJMCR. 2021; 5(12): 334-336. doi:
10.24911/ejmcr/173-1621160240
Meouchy PE, Bejjani N, Nader MA, Farah R. Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report. EJMCR. (2021), [cited April 18, 2024]; 5(12): 334-336. doi:
10.24911/ejmcr/173-1621160240
Meouchy, P. E., Bejjani, . N., Nader, . M. A. & Farah, . R. (2021) Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report. EJMCR, 5 (12), 334-336. doi:
10.24911/ejmcr/173-1621160240
Meouchy, Paul El, Noha Bejjani, Maroun Abou Nader, and Roula Farah. 2021. Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report. European Journal of Medical Case Reports, 5 (12), 334-336. doi:
10.24911/ejmcr/173-1621160240
Meouchy, Paul El, Noha Bejjani, Maroun Abou Nader, and Roula Farah. "Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report." European Journal of Medical Case Reports 5 (2021), 334-336. doi:
10.24911/ejmcr/173-1621160240
Meouchy, Paul El, Noha Bejjani, Maroun Abou Nader, and Roula Farah. "Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report." European Journal of Medical Case Reports 5.12 (2021), 334-336. Print. doi:
10.24911/ejmcr/173-1621160240
Meouchy, P. E., Bejjani, . N., Nader, . M. A. & Farah, . R. (2021) Germinoma occurring 9 years after surgical resection of a mature pineal teratoma: a case report. European Journal of Medical Case Reports, 5 (12), 334-336. doi:
10.24911/ejmcr/173-1621160240