Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient
Authors: Ugur Aferin, Berin Selcuk, Cansu Turker, Ovgu Aydin Ulgen, Hamdi Ozkara
Background: Kaposi’s sarcoma (KS) is a multifocal, angioproliferative malignant lesion originating from lymphatic endothelial cells. KS limited to the penis is extremely rare in human immunodeficiency virus (HIV) sero-negative patients. In this study, we aimed to present a case of isolated primary penile KS unrelated to HIV. Case Presentation: A 65-year-old man, with no risk factors for KS, presented with reddish nodules on penis. Biopsy was recommended to the patient for definitive diagnosis. Histopathological examination revealed that the diagnosis was classical type KS. No distant metastases were detected. No recurrence or disease progression was detected during the 4-year follow-up. Conclusion: Isolated primary penile KS is extremely rare in HIV sero-negative patients, but it should be kept in mind in the differential diagnosis of pigmented and nodular lesions in the penis. Excision of lesions with negative surgical margins has a high success and very low complication rate, as in our case.
Keywords: Kaposi sarcoma, penile nodule, HHV-8, penile lesion, HIV.
Authors
Correspondence to:
Ugur Aferin, TC Demiroglu Science University, Department of Urology, Istanbul, Turkey aferin.ugur@gmail.com
Publication history:
Received 17 May 2022
Accepted 02 Feb 2023
Published online 24 Mar 2023
Published in print 17 Apr 2023
Aferin U, Selcuk B, Turker C, Ulgen OA, Ozkara H. Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient. EJMCR. 2023; 7(4): 75-78. doi:
10.24911/ejmcr/173-1652790679
Aferin U, Selcuk B, Turker C, Ulgen OA, Ozkara H. Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient. https://www.ejmcr.com/?mno=38756 [Access: April 19, 2024]. doi:
10.24911/ejmcr/173-1652790679
Aferin U, Selcuk B, Turker C, Ulgen OA, Ozkara H. Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient. EJMCR. 2023; 7(4): 75-78. doi:
10.24911/ejmcr/173-1652790679
Aferin U, Selcuk B, Turker C, Ulgen OA, Ozkara H. Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient. EJMCR. (2023), [cited April 19, 2024]; 7(4): 75-78. doi:
10.24911/ejmcr/173-1652790679
Aferin, U., Selcuk, . B., Turker, . C., Ulgen, . O. A. & Ozkara, . H. (2023) Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient. EJMCR, 7 (4), 75-78. doi:
10.24911/ejmcr/173-1652790679
Aferin, Ugur, Berin Selcuk, Cansu Turker, Ovgu Aydin Ulgen, and Hamdi Ozkara. 2023. Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient. European Journal of Medical Case Reports, 7 (4), 75-78. doi:
10.24911/ejmcr/173-1652790679
Aferin, Ugur, Berin Selcuk, Cansu Turker, Ovgu Aydin Ulgen, and Hamdi Ozkara. "Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient." European Journal of Medical Case Reports 7 (2023), 75-78. doi:
10.24911/ejmcr/173-1652790679
Aferin, Ugur, Berin Selcuk, Cansu Turker, Ovgu Aydin Ulgen, and Hamdi Ozkara. "Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient." European Journal of Medical Case Reports 7.4 (2023), 75-78. Print. doi:
10.24911/ejmcr/173-1652790679
Aferin, U., Selcuk, . B., Turker, . C., Ulgen, . O. A. & Ozkara, . H. (2023) Unusual presentation of classical Kaposi Sarcoma: penile involvement in an HIV sero-negative patient. European Journal of Medical Case Reports, 7 (4), 75-78. doi:
10.24911/ejmcr/173-1652790679