Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report
Authors: Nadia Sharif, Sana Nasir, Niaz Hussain Soomro
Background: Bipolaris species are dematiaceous fungi that originally are plant pathogens but have been reported to cause a wide spectrum of diseases in both immunocompromised and immunocompetent human hosts. Case Presentation: We report a case of a young immunocompetent man who presented with fever, dry cough, and malaise. He had unilateral pleural effusion with mediastinal mass. Histopathology of pleura and mediastinal mass revealed granulomatous inflammation with fungal pseudohyphae. Tissue cultures grew Bipolaris species. He is on itraconazole with significant clinical improvement. Conclusion: This clinical presentation of Bipolaris infection has not been previously described. In Pakistan, where tuberculosis leuritis is frequently encountered, this case highlights that other rare causes of granulomatous pleuritis can also present in a similar fashion.
Keywords: Case report, Pheohyphomycosis, granulomatous pleuritis, Bipolaris infection.
Authors
Correspondence to:
Nadia Sharif, Assistant Professor, Ojha Institute of Chest Diseases, Department of Pulmonology,Dow University of Health Sciences, Karachi, Pakistan nadia.sharif66@gmail.com
Publication history:
Received 22 Sep 2021
Revised 20 Apr 2022
Accepted 22 May 2022
Published online 09 Aug 2022
Published in print 11 Sep 2022
Sharif N, Nasir S, Soomro NH. Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report. EJMCR. 2022; 6(5): 79-83. doi:
10.24911/ejmcr/173-1632298824
Sharif N, Nasir S, Soomro NH. Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report. https://www.ejmcr.com/?mno=126373 [Access: March 28, 2024]. doi:
10.24911/ejmcr/173-1632298824
Sharif N, Nasir S, Soomro NH. Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report. EJMCR. 2022; 6(5): 79-83. doi:
10.24911/ejmcr/173-1632298824
Sharif N, Nasir S, Soomro NH. Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report. EJMCR. (2022), [cited March 28, 2024]; 6(5): 79-83. doi:
10.24911/ejmcr/173-1632298824
Sharif, N., Nasir, . S. & Soomro, . N. H. (2022) Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report. EJMCR, 6 (5), 79-83. doi:
10.24911/ejmcr/173-1632298824
Sharif, Nadia, Sana Nasir, and Niaz Hussain Soomro. 2022. Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report. European Journal of Medical Case Reports, 6 (5), 79-83. doi:
10.24911/ejmcr/173-1632298824
Sharif, Nadia, Sana Nasir, and Niaz Hussain Soomro. "Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report." European Journal of Medical Case Reports 6 (2022), 79-83. doi:
10.24911/ejmcr/173-1632298824
Sharif, Nadia, Sana Nasir, and Niaz Hussain Soomro. "Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report." European Journal of Medical Case Reports 6.5 (2022), 79-83. Print. doi:
10.24911/ejmcr/173-1632298824
Sharif, N., Nasir, . S. & Soomro, . N. H. (2022) Bipolaris infection presenting as granulomatous pleuritis and mediastinal mass in a young immunocompetent man: a case report. European Journal of Medical Case Reports, 6 (5), 79-83. doi:
10.24911/ejmcr/173-1632298824