Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report
Authors: Nayyar Rubab, Muhammad Shahzad Afzal, Muhammad Shahbaz, Muhammad Babar Imran
Background: Papillary thyroid cancer (PTC) accounts for 90% of the thyroid malignancies with predominance in females. Distant metastasis is usually seen in lungs and bones. The treatment of metastatic papillary cancer thyroid is total/near total thyroidectomy followed by radioactive iodine (RAI) ablation. Lung metastasis shows a good response to RAI therapy. Case Presentation: We describe a case of a 22-year-old female, referred to the nuclear medicine department after surgery for RAI ablation. The patient was diagnosed case of PTC. The first dose of 100 mCi of RAI under steroid cover was given. The post-therapy scan showed bilateral pulmonary metastasis. However, follow-up I-131 whole-body imaging after 2 years showed no evidence of functioning thyroid tissue/metastasis. Conclusion: PTC with lung metastasis has a good prognosis and better survival in young patients treated with RAI. A single dose of RAI (I-131) may cure extensive lung metastasis.
Keywords: Papillary CA thyroid, Pulmonary metastasis, RAI ablation, Case report
Authors
Correspondence to:
Nayyar Rubab, PINUM Cancer Hospital, Faisalabad, Pakistan nayyar611@yahoo.com
Publication history:
Received 01 Sep 2021
Revised 14 Oct 2021
Accepted 22 Oct 2021
Published online 21 Dec 2021
Published in print 12 Jan 2022
Rubab N, Afzal MS, Shahbaz M, Imran MB. Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report. EJMCR. 2021; 5(12): 345-349. doi:
10.24911/ejmcr/173-1630476749
Rubab N, Afzal MS, Shahbaz M, Imran MB. Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report. https://www.ejmcr.com/?mno=118576 [Access: March 28, 2024]. doi:
10.24911/ejmcr/173-1630476749
Rubab N, Afzal MS, Shahbaz M, Imran MB. Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report. EJMCR. 2021; 5(12): 345-349. doi:
10.24911/ejmcr/173-1630476749
Rubab N, Afzal MS, Shahbaz M, Imran MB. Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report. EJMCR. (2021), [cited March 28, 2024]; 5(12): 345-349. doi:
10.24911/ejmcr/173-1630476749
Rubab, N., Afzal, . M. S., Shahbaz, . M. & Imran, . M. B. (2021) Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report. EJMCR, 5 (12), 345-349. doi:
10.24911/ejmcr/173-1630476749
Rubab, Nayyar, Muhammad Shahzad Afzal, Muhammad Shahbaz, and Muhammad Babar Imran. 2021. Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report. European Journal of Medical Case Reports, 5 (12), 345-349. doi:
10.24911/ejmcr/173-1630476749
Rubab, Nayyar, Muhammad Shahzad Afzal, Muhammad Shahbaz, and Muhammad Babar Imran. "Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report." European Journal of Medical Case Reports 5 (2021), 345-349. doi:
10.24911/ejmcr/173-1630476749
Rubab, Nayyar, Muhammad Shahzad Afzal, Muhammad Shahbaz, and Muhammad Babar Imran. "Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report." European Journal of Medical Case Reports 5.12 (2021), 345-349. Print. doi:
10.24911/ejmcr/173-1630476749
Rubab, N., Afzal, . M. S., Shahbaz, . M. & Imran, . M. B. (2021) Complete remission after primary single dose of radioactive iodine in metastatic papillary thyroid carcinoma: a case report. European Journal of Medical Case Reports, 5 (12), 345-349. doi:
10.24911/ejmcr/173-1630476749