Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report
Authors: Khalid Al Noaim, Amir Babiker, Angham Al Mutair, Mohsen Al Atawi, Mohammed Al Dubayee, Fahad Al Juraibah, Ibrahim Al Alwan
Background: Insulin overdose can result in fatal hypoglycemia. We report on a diabetic child who received an unintentional insulin overdose. Case presentation: A 13-year-old girl with type1 diabetes, who was on insulin pump therapy, developed high blood glucose (BG) level due to pump malfunction. She gave herself 7 ml (700 units) instead of 7 units by an error. She presented to hospital 2 hours later when this was recognized. The initial BG in the emergency room was 13.9 mmol/L. A dextrose infusion was started 6 hours after the insulin injections when her BG dropped significantly before it reached a lowest level of 3.3 mmol/L 9 hours after the event. It was only possible to discontinue this infusion 15 hours after insulin injections when BG was stable. Conclusion: Hypoglycemia could be delayed in insulin overdose in diabetic children. This may necessitate prolonged monitoring beyond the usual half-life of insulin.
Keywords: Insulin, overdose, delayed hypoglycemia, dextrose, glucagon, aspart, diabetes, case report
Authors
Correspondence to:
Khalid#Ibrahim#Al Noaim, College of Medicine, King Faisal University, Al Ahsa, Saudi Arabia kalnoaim@kfu.edu.sa; n3aaim@hotmail.com
Publication history:
Received 26 Apr 2019
Accepted 07 May 2019
Published in print 29 May 2019
Noaim KA, Babiker A, Mutair AA, Atawi MA, Dubayee MA, Juraibah FA, Alwan IA. Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report. EJMCR. 2019; 3(2): 91-94. doi:
10.24911/ejmcr/173-1556259277
Noaim KA, Babiker A, Mutair AA, Atawi MA, Dubayee MA, Juraibah FA, Alwan IA. Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report. https://www.ejmcr.com/?mno=45609 [Access: March 28, 2024]. doi:
10.24911/ejmcr/173-1556259277
Noaim KA, Babiker A, Mutair AA, Atawi MA, Dubayee MA, Juraibah FA, Alwan IA. Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report. EJMCR. 2019; 3(2): 91-94. doi:
10.24911/ejmcr/173-1556259277
Noaim KA, Babiker A, Mutair AA, Atawi MA, Dubayee MA, Juraibah FA, Alwan IA. Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report. EJMCR. (2019), [cited March 28, 2024]; 3(2): 91-94. doi:
10.24911/ejmcr/173-1556259277
Noaim, K. A., Babiker, . A., Mutair, . A. A., Atawi, . M. A., Dubayee, . M. A., Juraibah, . F. A. & Alwan, . I. A. (2019) Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report. EJMCR, 3 (2), 91-94. doi:
10.24911/ejmcr/173-1556259277
Noaim, Khalid Al, Amir Babiker, Angham Al Mutair, Mohsen Al Atawi, Mohammed Al Dubayee, Fahad Al Juraibah, and Ibrahim Al Alwan. 2019. Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report. European Journal of Medical Case Reports, 3 (2), 91-94. doi:
10.24911/ejmcr/173-1556259277
Noaim, Khalid Al, Amir Babiker, Angham Al Mutair, Mohsen Al Atawi, Mohammed Al Dubayee, Fahad Al Juraibah, and Ibrahim Al Alwan. "Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report." European Journal of Medical Case Reports 3 (2019), 91-94. doi:
10.24911/ejmcr/173-1556259277
Noaim, Khalid Al, Amir Babiker, Angham Al Mutair, Mohsen Al Atawi, Mohammed Al Dubayee, Fahad Al Juraibah, and Ibrahim Al Alwan. "Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report." European Journal of Medical Case Reports 3.2 (2019), 91-94. Print. doi:
10.24911/ejmcr/173-1556259277
Noaim, K. A., Babiker, . A., Mutair, . A. A., Atawi, . M. A., Dubayee, . M. A., Juraibah, . F. A. & Alwan, . I. A. (2019) Delayed hypoglycemic effect of insulin overdose in a diabetic child: a case report. European Journal of Medical Case Reports, 3 (2), 91-94. doi:
10.24911/ejmcr/173-1556259277