EJMCR. 2020; 4(5): 166-169

Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis

Authors: Vishal Mangal, Manish manrai, Ankit Kumar.

ABSTRACT

Background: Primary myelofibrosis is a rare myeloproliferative disorder that is occasionally associated with abdominal and hepatic complications, such as Budd–Chiari syndrome, nodular regenerative hyperplasia, portal vein thrombosis, and rarely portal hypertension, which is found in 7% of the cases. Case Presentation: We report a rare case of portal hypertension with chylous ascites in a 49-year-old male patient with primary myelofibrosis, who presented with a painless progressive distension of the abdomen for 1 month. His transjugular liver biopsy revealed extramedullary hematopoiesis with colonies of erythroid precursors, megakaryocytes, and numerous clusters of erythroid islands in the hepatic sinusoids. He was provided with a salt-restricted diet and diuretics with partial response and was scheduled for a transjugular intrahepatic portosystemic shunt. Conclusion: Extramedullary hematopoiesis should always be considered in patients with myeloproliferative disorders with a rare case of portal hypertension.

Keywords:
Myeloproliferative disorders, portal hypertension, chylous ascites, extramedullary hematopoiesis, primary myelofibrosis, case report


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Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis


Authors
Vishal Mangal
Clinical Tutor, Department of Medicine, Armed Forces Medical College, Pune, India
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Manish manrai
Assoc Professor, Department of Medicine, Armed Forces Medical College, Pune, India
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Ankit Kumar
Junior Resident, Department of Medicine, Armed Forces Medical College, Pune, India
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Correspondence to:
. Vishal Mangal, Department of Internal Medicine, Armed Forces Medical College, Pune, India.; vishal_rimshi@rediffmail.com

Publication history
Received 01 Mar 2020
Revised 07 May 2020
Accepted 18 May 2020
Published online 11 Jun 2020
Published in print 16 Jun 2020

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Pubmed Style

Mangal V, manrai M, Kumar A. Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis. EJMCR. 2020; 4(5): 166-169. doi:10.24911/ejmcr/173-1583099876


Web Style

Mangal V, manrai M, Kumar A. Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis. https://www.ejmcr.com/?mno=90021 [Access: July 11, 2020]. doi:10.24911/ejmcr/173-1583099876


AMA (American Medical Association) Style

Mangal V, manrai M, Kumar A. Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis. EJMCR. 2020; 4(5): 166-169. doi:10.24911/ejmcr/173-1583099876


Vancouver/ICMJE Style

Mangal V, manrai M, Kumar A. Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis. EJMCR. (2020), [cited July 11, 2020]; 4(5): 166-169. doi:10.24911/ejmcr/173-1583099876


Harvard Style

Mangal, V., manrai, . M. & Kumar, . A. (2020) Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis. EJMCR, 4 (5), 166-169. doi:10.24911/ejmcr/173-1583099876


Turabian Style

Mangal, Vishal, Manish manrai, and Ankit Kumar. 2020. Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis. European Journal of Medical Case Reports, 4 (5), 166-169. doi:10.24911/ejmcr/173-1583099876


Chicago Style

Mangal, Vishal, Manish manrai, and Ankit Kumar. "Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis." European Journal of Medical Case Reports 4 (2020), 166-169. doi:10.24911/ejmcr/173-1583099876


MLA (The Modern Language Association) Style

Mangal, Vishal, Manish manrai, and Ankit Kumar. "Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis." European Journal of Medical Case Reports 4.5 (2020), 166-169. Print. doi:10.24911/ejmcr/173-1583099876


APA (American Psychological Association) Style

Mangal, V., manrai, . M. & Kumar, . A. (2020) Extramedullary hematopoiesis causing portal hypertension with chylous ascites in a patient with primary myelofibrosis. European Journal of Medical Case Reports, 4 (5), 166-169. doi:10.24911/ejmcr/173-1583099876


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