Background: Ovarian cancer has emerged as one of the most common malignancies affecting women in India. Despite optimal surgery and appropriate first-line chemotherapy, almost 70%–80% of patients with epithelial ovarian cancer will develop recurrence. Inguinal lymph node metastasis is a rare site of involvement in recurrent epithelial ovarian cancer. Case Presentation: Herein, we report the case of a 54-year-old female who presented to us with painless left inguinal lymphadenopathy. She gave history of being diagnosed with malignant ovarian cancer 2 years ago, for which she underwent debulking surgery. She received only one cycle of chemotherapy after which she defaulted. Cytological examination of the inguinal nodes revealed metastatic ovarian cancer. CA-125 levels were elevated despite the lack of any foci of metabolically active tissue on imaging. Conclusion: Inguinal lymphadenopathy is a rare presentation of recurrent ovarian cancer. Despite that, it is essential to examine the inguinal region in the follow up of all the cases of ovarian cancer. It is also necessary to consider ovarian cancer in the differential diagnosis for inguinal lymphadenopathy in a female patient.

Keywords: Case report, ovarian carcinoma, recurrence, inguinal lymphadenopathy