EJMCR. 2020; 4(9): 292-295

Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus

Authors: Poh Sen Tay, Phyllis Wan Chun Ho.

ABSTRACT

Background: Acute necrotizing encephalopathy of childhood (ANEC) is a rare but distinctive type of encephalopathy predominantly involving infants and young children. This case report describes the characteristic neuroimaging findings which can aid in early diagnosis of ANEC. Case Presentation: An 11-year-old boy presented with a 2-day history of fever and flu-like illness and was given symptomatic treatment. He subsequently deteriorated on day 3 of illness with generalized tonic-clonic seizure and impaired consciousness. Magnetic resonance imaging done revealed abnormal signal intensities at bilateral thalami, brainstem, and cerebellum, which are suggestive of ANEC, correlating with his clinical presentation. Treatment was started immediately, but the patient had a very poor recovery. Conclusion: ANEC is a very rare encephalopathy and has very high mortality and morbidity with severe neurologic sequelae. Early diagnosis is important so that appropriate management can be provided.

Keywords:
Case report, acute necrotizing encephalopathy of childhood (ANEC), influenza A, H1N1.


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Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus


Authors
Poh Sen Tay
FRCR, Sarawak General Hospital, Kuching, Malaysia
PubMed articlesGoogle scholar articles

Phyllis Wan Chun Ho
FRCR, Sarawak General Hospital, Kuching, Malaysia
PubMed articlesGoogle scholar articles


Correspondence to:
. Poh Sen Tay, Radiologist, Sarawak General Hospital, Jalan Hospital, Sarawak, Malaysia.; pohsen@gmail.com

Publication history
Received 25 Nov 2019
Revised 20 Aug 2020
Accepted 14 Sep 2020
Published online 14 Oct 2020
Published in print 17 Oct 2020

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Pubmed Style

Tay PS, Ho PWC. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. EJMCR. 2020; 4(9): 292-295. doi:10.24911/ejmcr/173-1574570790


Web Style

Tay PS, Ho PWC. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. https://www.ejmcr.com/?mno=75047 [Access: October 23, 2020]. doi:10.24911/ejmcr/173-1574570790


AMA (American Medical Association) Style

Tay PS, Ho PWC. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. EJMCR. 2020; 4(9): 292-295. doi:10.24911/ejmcr/173-1574570790


Vancouver/ICMJE Style

Tay PS, Ho PWC. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. EJMCR. (2020), [cited October 23, 2020]; 4(9): 292-295. doi:10.24911/ejmcr/173-1574570790


Harvard Style

Tay, P. S. & Ho, . P. W. C. (2020) Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. EJMCR, 4 (9), 292-295. doi:10.24911/ejmcr/173-1574570790


Turabian Style

Tay, Poh Sen, and Phyllis Wan Chun Ho. 2020. Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. European Journal of Medical Case Reports, 4 (9), 292-295. doi:10.24911/ejmcr/173-1574570790


Chicago Style

Tay, Poh Sen, and Phyllis Wan Chun Ho. "Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus." European Journal of Medical Case Reports 4 (2020), 292-295. doi:10.24911/ejmcr/173-1574570790


MLA (The Modern Language Association) Style

Tay, Poh Sen, and Phyllis Wan Chun Ho. "Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus." European Journal of Medical Case Reports 4.9 (2020), 292-295. Print. doi:10.24911/ejmcr/173-1574570790


APA (American Psychological Association) Style

Tay, P. S. & Ho, . P. W. C. (2020) Acute necrotizing encephalopathy of childhood secondary to influenza A H1N1 virus. European Journal of Medical Case Reports, 4 (9), 292-295. doi:10.24911/ejmcr/173-1574570790


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