Recurrent biphasic pulmonary blastoma in a young patient: a case report
Authors: Nabila Javed, Asad Hayat Ahmad, Noorul Ain, Aakif Ullah Khan, Iftikhar Ahmad
Background: Biphasic pulmonary blastoma (BPB) is an uncommon and aggressive malignancy of the lung. Herein, we report a recurrent BPB in a young patient. Case Presentation: A 26-year-old female patient presented with respiratory distress and cough. Radiological workup illustrated well-circumscribed mass lesion (size ~ 6 cm) in the lateral basal segment of the lower lobe of the right lung, for which the patient underwent lobectomy. Histopathology revealed BPB. The patient was kept on close follow-up without any oncological intervention and remained disease-free for 3 years. Afterward, the patient presented with recurrent disease (i.e., a pulmonary oval nodule of size ~ 1.4 ×1.2 cm) and metastasis in the right renal region with infiltration into the right T12-LV1 and LV2 vertebrae. The patient was given three courses of multi-agent chemotherapy (i.e., ifosfamide, carboplatin, and etoposide), which resolved the pulmonary lesion only. Conclusion: Ultimately, our study indicates that BPB is an aggressive disease and demands multimodality treatment toward favorable prognosis.s.
Keywords: Biphasic pulmonary blastoma, chemotherapy, ICE, lobectomy, case report
Authors
Correspondence to:
Iftikhar Ahmad, Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan iahmadmp@gmail.com
Publication history:
Received 19 Jan 2019
Revised 14 Oct 2019
Accepted 15 Oct 2019
Published online 31 Dec 2019
Published in print 12 Feb 2020
Javed N, Ahmad AH, Ain N, Khan AU, Ahmad I. Recurrent biphasic pulmonary blastoma in a young patient: a case report. EJMCR. 2020; 4(1): 4-8. doi:
10.24911/ejmcr/173-1547876436
Javed N, Ahmad AH, Ain N, Khan AU, Ahmad I. Recurrent biphasic pulmonary blastoma in a young patient: a case report. https://www.ejmcr.com/?mno=26997 [Access: April 25, 2024]. doi:
10.24911/ejmcr/173-1547876436
Javed N, Ahmad AH, Ain N, Khan AU, Ahmad I. Recurrent biphasic pulmonary blastoma in a young patient: a case report. EJMCR. 2020; 4(1): 4-8. doi:
10.24911/ejmcr/173-1547876436
Javed N, Ahmad AH, Ain N, Khan AU, Ahmad I. Recurrent biphasic pulmonary blastoma in a young patient: a case report. EJMCR. (2020), [cited April 25, 2024]; 4(1): 4-8. doi:
10.24911/ejmcr/173-1547876436
Javed, N., Ahmad, . A. H., Ain, . N., Khan, . A. U. & Ahmad, . I. (2020) Recurrent biphasic pulmonary blastoma in a young patient: a case report. EJMCR, 4 (1), 4-8. doi:
10.24911/ejmcr/173-1547876436
Javed, Nabila, Asad Hayat Ahmad, Noorul Ain, Aakif Ullah Khan, and Iftikhar Ahmad. 2020. Recurrent biphasic pulmonary blastoma in a young patient: a case report. European Journal of Medical Case Reports, 4 (1), 4-8. doi:
10.24911/ejmcr/173-1547876436
Javed, Nabila, Asad Hayat Ahmad, Noorul Ain, Aakif Ullah Khan, and Iftikhar Ahmad. "Recurrent biphasic pulmonary blastoma in a young patient: a case report." European Journal of Medical Case Reports 4 (2020), 4-8. doi:
10.24911/ejmcr/173-1547876436
Javed, Nabila, Asad Hayat Ahmad, Noorul Ain, Aakif Ullah Khan, and Iftikhar Ahmad. "Recurrent biphasic pulmonary blastoma in a young patient: a case report." European Journal of Medical Case Reports 4.1 (2020), 4-8. Print. doi:
10.24911/ejmcr/173-1547876436
Javed, N., Ahmad, . A. H., Ain, . N., Khan, . A. U. & Ahmad, . I. (2020) Recurrent biphasic pulmonary blastoma in a young patient: a case report. European Journal of Medical Case Reports, 4 (1), 4-8. doi:
10.24911/ejmcr/173-1547876436