EJMCR. 2018; 2(3): 91-94

Three case reports of chronic pain with neuropathic component - the importance of individualized therapy

Authors: Filipa Ferreira Pereira, Sergio Azevedo, Helena Magalhaes, Claudia Vieira, Deolinda Pereira, Maria Fragoso.

ABSTRACT

Background: Pain is the most common symptom present at any stage of life. The pain can be divided into acute or chronic considering the duration of symptoms. Chronic pain approach is complex and it is a clinical challenge. Two main mechanisms are traditionally described: pain nociceptive (caused by ongoing tissue damage, somatic, or visceral) or neuropathic (damage or dysfunction in the nervous system). For the treatment of chronic moderate-severe pain, opioids are the standard treatment but the undesirable side effects cause a high discontinuation rate. Tapentadol was developed to improve the therapeutic range of opioids by adding two complementary mechanisms of action which seem to contribute to the reduction of side effects. Case Presentation: The authors describe three cases of neuropathic chronic pain. One case describes neuropathic pain caused by degenerative changes and osteoporotic fracture, the second case was a woman with an important renal impairment, who complained of generalized arthralgia (under cancer treatment), and a third case of a man presented with diminished muscle strength in the lower right limb, most probably due to chemotherapy-induced peripheral neuropathy. Conclusion: The management of chronic pain requires a multimodal approach, that is part of the individual as a whole, and a multidisciplinary approach is needed to relieve chronic pain with minimal side effects.

Keywords:
Pain, neuropathic pain, cancer, analgesics, opioid, case report


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Three case reports of chronic pain with neuropathic component - the importance of individualized therapy


Authors
Filipa Ferreira Pereira
Rua Dr. António Bernardino de Almeida 4200-072 Porto, Portugal
PubMed articlesGoogle scholar articles

Sergio Azevedo
Rua Dr. António Bernardino de Almeida 4200-072 Porto, Portugal
PubMed articlesGoogle scholar articles

Helena Magalhaes
Rua Dr. António Bernardino de Almeida 4200-072 Porto, Portugal
PubMed articlesGoogle scholar articles

Claudia Vieira
Rua Dr. António Bernardino de Almeida 4200-072 Porto, Portugal
PubMed articlesGoogle scholar articles

Deolinda Pereira
Rua Dr. António Bernardino de Almeida 4200-072 Porto, Portugal
PubMed articlesGoogle scholar articles

Maria Fragoso
Rua Dr. António Bernardino de Almeida 4200-072 Porto, Portugal
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Correspondence to:
. Filipa Ferreira Pereira, Rua Dr. António Bernardino de Almeida 4200-072 Porto, Portugal; filipa.mfp@gmail.com

Publication history
Received 04 Aug 2018
Accepted 31 Aug 2018
Published in print 12 Oct 2018

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Pubmed Style

Pereira FF, Azevedo S, Magalhaes H, Vieira C, Pereira D, Fragoso M. Three case reports of chronic pain with neuropathic component - the importance of individualized therapy. EJMCR. 2018; 2(3): 91-94. doi:10.24911/ejmcr/173-1532985971


Web Style

Pereira FF, Azevedo S, Magalhaes H, Vieira C, Pereira D, Fragoso M. Three case reports of chronic pain with neuropathic component - the importance of individualized therapy. http://www.ejmcr.com/?mno=1196 [Access: November 15, 2018]. doi:10.24911/ejmcr/173-1532985971


AMA (American Medical Association) Style

Pereira FF, Azevedo S, Magalhaes H, Vieira C, Pereira D, Fragoso M. Three case reports of chronic pain with neuropathic component - the importance of individualized therapy. EJMCR. 2018; 2(3): 91-94. doi:10.24911/ejmcr/173-1532985971


Vancouver/ICMJE Style

Pereira FF, Azevedo S, Magalhaes H, Vieira C, Pereira D, Fragoso M. Three case reports of chronic pain with neuropathic component - the importance of individualized therapy. EJMCR. (2018), [cited November 15, 2018]; 2(3): 91-94. doi:10.24911/ejmcr/173-1532985971


Harvard Style

Pereira, F. F., Azevedo, . S., Magalhaes, . H., Vieira, . C., Pereira, . D. & Fragoso, . M. (2018) Three case reports of chronic pain with neuropathic component - the importance of individualized therapy. EJMCR, 2 (3), 91-94. doi:10.24911/ejmcr/173-1532985971


Turabian Style

Pereira, Filipa Ferreira, Sergio Azevedo, Helena Magalhaes, Claudia Vieira, Deolinda Pereira, and Maria Fragoso. 2018. Three case reports of chronic pain with neuropathic component - the importance of individualized therapy. European Journal of Medical Case Reports, 2 (3), 91-94. doi:10.24911/ejmcr/173-1532985971


Chicago Style

Pereira, Filipa Ferreira, Sergio Azevedo, Helena Magalhaes, Claudia Vieira, Deolinda Pereira, and Maria Fragoso. "Three case reports of chronic pain with neuropathic component - the importance of individualized therapy." European Journal of Medical Case Reports 2 (2018), 91-94. doi:10.24911/ejmcr/173-1532985971


MLA (The Modern Language Association) Style

Pereira, Filipa Ferreira, Sergio Azevedo, Helena Magalhaes, Claudia Vieira, Deolinda Pereira, and Maria Fragoso. "Three case reports of chronic pain with neuropathic component - the importance of individualized therapy." European Journal of Medical Case Reports 2.3 (2018), 91-94. Print. doi:10.24911/ejmcr/173-1532985971


APA (American Psychological Association) Style

Pereira, F. F., Azevedo, . S., Magalhaes, . H., Vieira, . C., Pereira, . D. & Fragoso, . M. (2018) Three case reports of chronic pain with neuropathic component - the importance of individualized therapy. European Journal of Medical Case Reports, 2 (3), 91-94. doi:10.24911/ejmcr/173-1532985971


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